By Martine Extermann MD, Lodovico Balducci, William B. Ershler, Gary H. Lyman, Martine Extermann
The prevention and therapy of melanoma in older sufferers calls for an individualized method, as age factors unpredictable effects from sufferer to sufferer. thoroughly revised and up to date, this moment variation of a bestseller allows clinicians to settle on the absolute best melanoma care. Highlighting rising matters in geriatric oncology, it is helping physicians advertise melanoma prevention and exhaustively stories the biology of melanoma and getting older, epidemiologic developments, and scientific trials. New chapters comprise fabric on issues reminiscent of review, fragility, symptom administration, and emergencies, and reviews of the effectiveness of teaching courses in geriatric oncology.
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Metaanalysis. Proc Am Soc Clin Oncol 2000; 19:241a (Abst 933). 19. Cohen HJ, Cox E, Manton K, Woodbury M. Malignant melanoma in the elderly. J Clin Oncol 1987; 5:100–6. 20. Boffeta P, Parkin DM. Cancer in developing countries. CA Cancer J Clin 1994; 44:81–90. 21. Schiffer CA, Mclntyre OR. Age related changes in adults with acute leukemia. In: The Underlying Molecular, Cellular. and Immunological Factors in Cancer and Aging (Yang SS, Warner HR, eds). New York: Plenum Press, 1993:215–29. 22. Balducci L, Yates J.
Aging and cancer Increasing age represents the single most important risk factor for cancer. 3, the number of cancer deaths in the USA peaks between the ages of 65 and 75 and then decreases owing to competing risks for mortality in the declining population at risk. 4). 3 Graphic display of cancer incidence rates and the number of new cases for the US population by 5-year Comprehensive Geriatric Oncology 28 age group for the period 1973–98. The cancer incidence rate per 100000 individuals per year is displayed as a line graph while the numbers of new cases (×100) are represented by the vertical bars.
There is more squamous cell cancer in patients over 70 (71%) than in those under 50 (58%), which may reflect the less advanced stage of the disease in older patients. Although older persons may have a greater risk of early death after thoracotomy, the likelihood of long-term survival following surgery is not diminished by age alone. Hence, the risk of surgery is well worth the benefit in selected patients. Older patients fare just as well as younger ones with radiotherapy or palliative chemotherapy.