By Peter A. Lichtenberg
Huge, interdisciplinary consultant to figuring out diagnosing, and treating dementia and its comparable health problems and stipulations. presents really expert wisdom concerning the mental, neurological, and psychiatric points of dementia, together with etiology and analysis, evaluation instruments, remedies, and comorbidities. additionally addresses multicultural matters. DNLM: Dementia.
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Additional info for HANDBOOK OF DEMENTIA Psychological, Neurological,and Psychiatric Perspectives
Inhibitors of ß-secretase are in the preclinical phases of investigation. Despite their shortcomings, the availability of transgenic mouse models of AD that develop age-dependent progressive amyloid deposition in brain and cognitive decline has greatly facilitated development of putative AD therapeutics. Whether any of these therapies will be useful for humans, however, remains to be seen. Because of inflammatory responses to amyloid in AD brain tissue, it was hypothesized that immunization of human APP transgenic mice with Αß may exacerbate disease.
Et al. (2001). Practice parameter: Management of dementia (an evidencebased review). Neurology, 56, 1154–1166. 22 Neurologic Aspects of Alzheimer’s Disease Evans, D. , Funkenstein, H. , Albert, M. , Scherr, P. , Cook, N. , Chown, M. , et al. (1989). Prevalence of Alzheimer’s disease in a community population of older persons. Higher than previously reported. Journal of the American Medical Association, 262, 2551–2556. Evenhuis, H. M. (1990). The natural history of dementia in Down’s syndrome.
The presence of sensory loss or premorbid conditions can challenge the neuropsychologist because no appropriate normative data may be available. An alternative approach to evaluation in such cases is to demonstrate relative strengths in old knowledge and skills in the presence of specific deficits in areas that are most often deficient in AD as described previously. ASSESSING FUNCTION: EVALUATION OF INSTRUMENTAL AND BASIC ACTIVITIES OF DAILY LIVING There are many instruments that capture functional deterioration.