Download Molecular mechanisms of skin aging and age-related diseases by Taihao Quan PDF

By Taihao Quan

Our pores and skin alterations as we age. It turns into thinner and loses fats, making it much less plump and soft. Clinically, elderly pores and skin is characterised by means of wrinkles, sagging, age spots and dryness. Emphasizing laboratory and medical examine, this e-book comprehensively describes the molecular mechanisms of human skin-aging and age-related epidermis illnesses. This contains molecular knowing of the advance of getting older pores and skin and its prevention in addition to mechanisms-based medical rejuvenation. The e-book additionally makes a speciality of study to strengthen mechanisms-based anti-skin-aging products.

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A. Young. 2006. Age-related macular degeneration: a practical approach to a challenging disease. J Am Geriatr Soc 54: 1130-1135. H. G. Smith and D. Davignon. 1996. Increased mortality associated with diabetic foot ulcer. Diabet Med: a journal of the British Diabetic Association 13: 967-972. , H. C. Nerusu, N. Bhagavathula, S. J. Fisher, et al. 2003. Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochem Photobiol 78: 43-48.

E. non-melanoma) skin cancer, which is the most common form of cancer in the USA. For example, one in five Americans will develop skin cancer in the course of a lifetime and 40-50% of Americans who lives to age 65 will have skin cancer at least once (Gloster and Brodland 1996; Kahlos et al. ), 2005). Ultraviolet (UV) irradiation from the sun is a key initiating factor for development of most keratinocyte skin cancer. UV irradiation causes DNA damage that can lead to mutations, which can accumulate as a result of repeated sun exposures.

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